Dr Alexander Lyon, Imperial College & Royal Brompton Hospital, London, UK
Cardio Debate talks to Dr Alexander Lyon about his presentation in the Heart Failure section during the Cardiology Update 2016 meeting, organised by St George’s, University of London on the 2nd December 2016 at the RSA in London, UK.


My name is Dr Alexander Lyon, I’m a senior lecturer at Imperial College, London, UK, and a honorary consultant cardiologist at the Royal Brompton Hospital in London. I’m also a member of the Heart Failure Association Board with specialist interest in cardio-oncology and heart failure caused by cancer drugs, and also Takotsubo syndrome and stress and the interaction of heart failure.

Which were the most salient aspects of your talk?

I had the privilege and challenge of discussing heart failure with preserved ejection fraction (HFpEF) which is a growing clinical problem for our health care services, but we’re limited in terms of our understanding of this condition and therefore how we can treat it.

I reviewed some of the information about some of the mechanisms. I personally believe there are many different subtypes of this condition. So whereas with heart failure with reduced ejection fraction patients we’ve had success using some common treatments across them all irrespective of etiology, when we move into HFpEF we haven’t been successful with the ‘one size fits all’ common pathways.

So therefore we need to do more research to understand particular types of patients, not least related to their comorbidities. So I discussed how comorbidities are and the different ‘flavours’ of HFpEF, and from that then we can start to understand the biology of each one, and personalise treatment approaches.

And I finished by giving some real world advice on what we can do with the patients today whilst we still need further research on how to manage the patient of tomorrow better.